Most likely your Antivirus (AV) or Microsoft Defender has deleted it. Make sure to add an exception for the following files: excavator.exe,NiceHashQuickMiner.exe andxmrig.exe
This can cause mining failure. Increase your Virtual Memory size to at least 6000 MB times the number of GPUs your PC has. Read here how to increase Virtual Memory size.
MSI is not enabled. Read how to enable it here. Message Signaled Interrupts is a method of CPU-GPU communication. Wiki states that:
When activating MSI, you can actually notice that your GPU will is more stable. Especially if your GPU crashes here and there due to high OC values, the crash will be easily recoverable without PC restart and other GPUs will not be so drastically affected. Without MSI enabled, a crash of a single GPU usually results in a blue screen of the entire OS thus reboot of the PC
Notice: Enabling MSI might cause issues with LHR unlock.
This error means that QuickMiner cannot communicate with Excavator. Potential solutions: