NiceHash does support the AsicBoost protocol. If you want to mine with the AsicBoost protocol, you must connect your ASIC to a separate SHA256AsicBoost stratum.
Mining with AsicBoost on the ordinary SHA256 stratum will not work.
You can generate the stratum address on our stratum generator.
We offer white-glove support to mining farms with 100 or more workers. Please write to farm@nicehash.com if you have any additional questions.